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Table 3 Pairwise comparisons of variation at different codon positions in reovirus genome segments

From: Comparisons of the M1 genome segments and encoded μ2 proteins of different reovirus isolates

  

Variation (%) in the long open reading frame of genome segment

Codon position

Isolate pair

L1

L2

L3

M1

M2

M3

S2

S3

S4

firsta

T1L:T2J

16.9

19.9

12.2

24.6

11.1

25.3

13.7

25.5

13.1

 

T2J:T3D

16.7

20.4

12.7

26.1

10.7

25.0

14.0

25.5

13.9

 

T1L:T3D

2.4

15.4

1.4

1.5

6.0

7.6

6.1

6.6

4.0

seconda

T1L:T2J

5.3

8.0

3.3

11.8

1.7

10.0

4.1

8.4

5.1

 

T2J:T3D

5.1

7.5

3.2

11.8

1.7

9.6

4.1

8.0

5.5

 

T1L:T3D

0.8

3.5

0.3

0.4

2.1

2.0

0.0

2.2

1.1

thirda

T1L:T2J

77.1

83.7

79.4

80.1

81.5

81.2

74.0

79.1

73.8

 

T2J:T3D

76.7

77.4

79.1

81.0

82.7

83.0

73.0

73.9

76.7

 

T1L:T3D

12.9

76.1

7.5

6.5

53.3

39.2

53.6

48.1

21.9

syn.b

T1L:T2J

88.3

90.2

89.6

85.8

90.0

87.1

83.8

90.2

81.9

 

T2J:T3D

87.5

84.2

89.3

87.0

89.3

89.8

83.6

85.4

84.2

 

T1L:T3D

15.0

85.9

8.8

7.9

59.3

46.4

63.1

58.2

25.8

nonsyn.b

T1L:T2J

5.9

9.1

3.8

12.6

2.6

11.8

4.8

10.2

6.2

 

T2J:T3D

5.9

8.9

3.9

13.1

3.2

11.5

4.7

9.6

6.8

 

T1L:T3D

0.8

5.0

0.3

0.5

1.2

2.0

0.7

1.3

1.3

cons.c

T1L:T2J

60.0

66.3

57.1

63.8

50.0

60.6

50.0

60.8

73.5

  

5.0

8.7

2.5

12.2

1.3

10.7

2.9

8.5

6.8

 

T2J:T3D

62.7

64.5

56.1

64.6

65.2

60.5

52.0

60.8

71.1

  

5.1

8.6

2.5

12.9

2.1

10.0

3.1

8.5

7.4

 

T1L:T3D

36.4

77.4

88.9

80.0

50.0

62.5

100

40.0

63.6

  

0.6

5.6

0.6

1.1

1.1

2.8

1.2

1.0

1.9

noncon.c

T1L:T2J

18.1

10.7

17.9

17.0

11.1

18.9

20.8

17.6

14.7

  

1.5

1.4

0.8

3.3

0.3

3.3

1.2

2.5

1.4

 

T2J:T3D

18.6

9.9

19.3

16.3

13.0

16.8

20.0

15.7

21.1

  

1.5

1.3

0.9

3.3

0.4

2.8

1.2

2.2

2.2

 

T1L:T3D

18.2

8.6

11.1

0.0

12.5

3.1

0.0

20.0

27.3

  

0.3

0.6

0.1

0.0

0.3

0.1

0.0

0.5

0.8

  1. S1 not included because of uncertainty in where to place gaps.
  2. a Values determined for each pairwise comparison as: # base changes / total such positions × 100.
  3. b Values determined as # of observed changes/ # of positions at which changes could have occurred × 100.
  4. c Upper value indicates proportion of all amino acid substitutions that are conservative or nonconservative (using CLUSTAL W analysis with BLOSUM weighting); semi-conservative substitutions not included. Lower bold value indicates proportion of indicated types of alterations as a percentage of total number of amino acids within whole protein.