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Table 3 Induction Ratio (HSV+/Mock) of Transcripts for Chemokine Receptors, Chemokines and Cytokines in Cornea and Trigeminal Ganglia (TG)

From: Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection

 

Corneaa

TGb

Gene

3d

10d

30d

3d

10d

30d

CCR1

11 (9.2–12)

18 (13–23)

20 (10–26)

5 (2.2–7.1)

15 (9.0–19)

4 (1.7–7.0)

CCR2

14 (9.2–19)

22 (11–32)

14 (8.1–24)

3 (1.5–4.2)

15 (11–19)

3 (1.3–4.4)

CCR3

2 (1.0–5.0)

3 (2.0–5.0)

3 (2.5–3.3)

2 (0.5–5.0)

8 (2.2–20)

3 (1.8–4.7)

CCR5

12 (12.3–12.5)

11 (8.0–14)

20 (8.9–36)

9 (4.8–11)

57 (22–110)

9 (7.0–10)

CCR6

3 (2.4–3.0)

2 (1.0–2.5)

5 (1.5–8.5)

3 (0.3–11)

3 (1.0–5.0)

14 (1.0–40)

CCR7

24 (8.0–40)

5 (3.0–6.5)

17 (13–21)

13 (9.0–17)

19 (17–20)

7 (2.0–11)

CXCR3

10 (5.0–18)

15 (8.0–23)

5 (2.8–6.5)

2 (1.0–4.0)

104 (54–160)

36 (14–59)

CXCR4

11 (4.8–14)

3 (1.7–4.0)

45 (33–74)

0.6 (0.4–0.9)

4 (2.9–6.2)

3 (2.3–3.7)

MIP-1α

69 (33–106)

394 (263–1700)

34 (16–53)

232 (80–471)

126 (80–168)

25 (13–45)

MIP-1β

53 (39–67)

285 (261–310)

16 (11–21)

282 (10–595)

230 (202–245)

31 (24–37)

RANTES

55 (36–73)

43 (38–48)

16 (12–18)

64 (61–66)

304 (302–306)

31 (12–50)

MCP-1

54 (52–55)

64 (55–74)

12 (7.5–20)

153 (113–194)

22 (16–27)

3 (1.6–4.2)

Eotaxin-1

3 (1.9–3.5)

1 (0.6–1.3)

3 (1.0–5.4)

5 (3.3–9.1)

2 (1.2–2.8)

1.5 (0.7–2.3)

IFNγ

Inf.c

Inf.

Inf.

Inf.

Inf.

Inf.

TNF-α

3 (2.9–3.0)

3 (2.6–3.8)

7 (3.9–12)

Inf.

Inf.

Inf.

  1. a Induction ratios were calculated as relative expression in HSV-infected/relative expression in mock-infected cornea. Each value is the average of induction ratios (2 or 3 separate measurements per cDNA sample) from two independent experiments. Ranges of individual ratios are in parentheses.
  2. b Induction ratios were calculated for HSV- vs. mock-infected TG as in footnote a. Each value is the average of induction ratios (2 or 3 separate measurements per cDNA sample) from three independent experiments, with ranges in parentheses.
  3. c Inf., infinite due to relative expression = 0 in all or most mock-infected samples.