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Table 2 Prevention of GH in guinea pigs by DL11 scFv.

From: Prevention of genital herpes in a guinea pig model using a glycoprotein D-specific single chain antibody as a microbicide

Pre-treatment

Severity of lesions

Mean lesion score (n = 20)

500 µg/ml DL2 scFv 20 minutes prior to infection

2, 2, 3, 3, 3, 3, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4.

3.55 ± 0.153 *

500 µg/ml DL11 scFv 20 minutes prior to infection

0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0. 0, 0, 0, 3.

0.15 ± 0.15 *

  1. * p < 0.0001 (Mann-Whitney test)
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Virology Journal

ISSN: 1743-422X