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Figure 8 | Virology Journal

Figure 8

From: Prevention of genital herpes in a guinea pig model using a glycoprotein D-specific single chain antibody as a microbicide

Figure 8

Effect of DL11 scFv on HSV-1 genital disease in guinea pigs. Panel A: Blisters of GH 5 days after instillation of HSV-1 into vaginal vault. Several areas of ulceration with surrounding erythema are visible bilaterally (e.g. arrows); Panel B: Complete protection against HSV-1 by prior instillation, immediately before HSV challenge, of 1 ml CMC containing DL11 scFv (500 µg/ml).

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Virology Journal

ISSN: 1743-422X